rucaparib


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111 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 136
2 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 61
3 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 19
4 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 11
5 poly(ADP-ribose) polymerase 2 PARP2_HUMAN PARP2 Homo sapiens 10038 107 7
6 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 7
7 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 7
8 poly(ADP-ribose) polymerase family member 3 PARP3_HUMAN PARP3 Homo sapiens 10039 44 5
9 RAD51 paralog C RA51C_HUMAN RAD51C Homo sapiens 5889 22 4
10 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 4
11 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 4
12 partner and localizer of BRCA2 PALB2_HUMAN PALB2 Homo sapiens 79728 35 3
13 cytochrome P450 family 2 subfamily C member 19 CP2CJ_HUMAN CYP2C19 Homo sapiens 1557 1098 2
14 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 2
15 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 2
16 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 2
17 ADP-ribosyltransferase 1 NAR1_HUMAN ART1 Homo sapiens 417 42 2
18 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase G6PE_HUMAN H6PD Homo sapiens 9563 280 2
19 myosin light chain kinase MYLK_HUMAN MYLK Homo sapiens 4638 298 2
20 poly(ADP-ribose) polymerase family member 4 PARP4_HUMAN PARP4 Homo sapiens 143 12 2
21 ETS transcription factor ERG ERG_HUMAN ERG Homo sapiens 2078 1044 2
22 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 2
23 protein tyrosine kinase 2 beta FAK2_HUMAN PTK2B Homo sapiens 2185 848 2
24 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 2
25 RAD51 paralog D RA51D_HUMAN RAD51D Homo sapiens 5892 37 2
26 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 2
27 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
28 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 2
29 cyclin dependent kinase 9 CDK9_HUMAN CDK9 Homo sapiens 1025 239 1
30 sirtuin 1 SIR1_HUMAN SIRT1 Homo sapiens 23411 1253 1
31 cytochrome P450 family 2 subfamily D member 6 CP2D6_HUMAN CYP2D6 Homo sapiens 1565 1531 1
32 twinkle mtDNA helicase PEO1_HUMAN TWNK Homo sapiens 56652 180 1
33 POU class 2 homeobox 2 PO2F2_HUMAN POU2F2 Homo sapiens 5452 995 1
34 deoxycytidine kinase DCK_HUMAN DCK Homo sapiens 1633 234 1
35 glutamic--pyruvic transaminase ALAT1_HUMAN GPT Homo sapiens 2875 774 1
36 epithelial cell adhesion molecule EPCAM_MOUSE Epcam Mus musculus 17075 73 1
37 cytochrome P450 family 2 subfamily C member 8 CP2C8_HUMAN CYP2C8 Homo sapiens 1558 590 1
38 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 1
39 phosphoglycolate phosphatase PGP_MOUSE Pgp Mus musculus 67078 756 1
40 poly(ADP-ribose) polymerase family member 15 PAR15_HUMAN PARP15 Homo sapiens 165631 48 1
41 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 1
42 interferon alpha 1 IFNA1_HUMAN IFNA1 Homo sapiens 3439 1490 1
43 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 1
44 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 1
45 transmembrane serine protease 2 TMPS2_HUMAN TMPRSS2 Homo sapiens 7113 244 1
46 POU class 2 homeobox 1 PO2F1_HUMAN POU2F1 Homo sapiens 5451 98 1
47 sirtuin 3 SIR3_HUMAN SIRT3 Homo sapiens 23410 319 1
48 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 1
49 Wnt family member 3A WNT3A_HUMAN WNT3A Homo sapiens 89780 293 1
50 solute carrier organic anion transporter family member 1B1 SO1B1_HUMAN SLCO1B1 Homo sapiens 10599 575 1